TREML2 Protein (His tag)

Catalog No. ABIN7320674

This Recombinant TREML2 protein is expressed in Human Cells.

Quick Overview for TREML2 Protein (His tag) (ABIN7320674)

Target: TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purity: > 95 % as determined by SDS-PAGE

Product Details

Purification tag / Conjugate: This TREML2 protein is labelled with His tag.

Purpose: Recombinant Mouse TREML2/TLT2 Protein (His Tag)

Sequence: His25-Ala270

Characteristics: Recombinant Mouse Triggering Receptor Expressed on Myeloid Cells-like Protein 2 is produced by our Mammalian expression system and the target gene encoding His25-Ala270 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))

Alternative Name: TREML2/TLT2

Background:

Background: Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, which can be induced in CD4 T-cell by concanavalin-A. As a cell surface receptor, TREML2 may play a role in the innate and adaptive immune response. TREML2 also acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. It has shown that TREML2 may be involved in the innate immune response based on its expression profile and the fact that it is up-regulated in response to inflammation.

Synonym: Trem-like transcript 2 protein, TLT-2, Triggering receptor expressed on myeloid cells-like protein 2, TREML2, TLT2

Molecular Weight: 28.4 kDa

UniProt: Q2LA85