Quick Overview for TPBG Protein (mFc Tag) (ABIN7319827)
Target
See all TPBG ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This TPBG protein is labelled with mFc Tag.
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Purpose
- Recombinant Human TPBG/5T4 (C-mFc)
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Sequence
- Ser32-Ser355
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Characteristics
- Recombinant Human Trophoblast glycoprotein is produced by our Mammalian expression system and the target gene encoding Ser32-Ser355 is expressed with a mFc tag at the C-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Trophoblast Glycoprotein (TPBG) (AA 32-355) protein (His-Avi Tag,Biotin)
TPBG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Trophoblast Glycoprotein (TPBG) (AA 32-355) protein (His tag)TPBG Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Trophoblast Glycoprotein (TPBG) (AA 32-355) protein (His-Avi Tag)TPBG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Trophoblast Glycoprotein (TPBG) (AA 32-361) protein (His tag)TPBG Origin: Mouse Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Trophoblast Glycoprotein (TPBG) (AA 1-420) protein (GST tag)TPBG Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Trophoblast Glycoprotein (TPBG) (AA 35-355) protein (His tag)TPBG Origin: Cynomolgus Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Trophoblast Glycoprotein (TPBG) protein (His tag,Biotin)TPBG Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Trophoblast Glycoprotein (TPBG) (AA 32-355) protein (FITC,His-Avi Tag)TPBG Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Trophoblast Glycoprotein (TPBG) (AA 32-355) protein (His tag,AVI tag)TPBG Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- TPBG (Trophoblast Glycoprotein (TPBG))
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Alternative Name
- TPBG/5T4
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Background
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Background: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
Synonym: 5T4 , 5T4AG, M6P1, WAIF1
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Molecular Weight
- 61.7 kDa
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UniProt
- Q13641
Target
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