UBE2G2 Protein (GST tag)
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- Target See all UBE2G2 Proteins
- UBE2G2 (Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBE2G2 protein is labelled with GST tag.
- Purpose
- Recombinant Human UBE2G2 Protein (GST Tag)
- Sequence
- Met 1-Leu165
- Characteristics
- Recombinant Human Ubiquitin-Conjugating Enzyme E2 G2 is produced by our E.coli expression system and the target gene encoding Met1-Leu165 is expressed with a GST tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (AA 1-165) protein (His tag)
UBE2G2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) proteinUBE2G2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (AA 1-165) protein (GST tag)UBE2G2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (Transcript Variant 1) protein (His tag)UBE2G2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBE2G2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10 % Glycerol, pH 7.5.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- UBE2G2 (Ubiquitin-Conjugating Enzyme E2G 2 (UBE2G2))
- Alternative Name
- UBE2G2 (UBE2G2 Products)
- Background
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Background: Ubiquitin-Conjugating Enzyme E2 G2 (UBE2G2) is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation, which belong to the ubiquitin-conjugating enzyme family. It shares 60 % and 100 % sequence identity with S.cerevisiae Ubc7 and mouse respectively. The UBE2G2 enzyme and the GP78 E3 ligase are active components of endoplasmic reticulum-associated degradation pathway which is essential for the degradation of misfolded ER proteins. The mechanism of K48-linked poly-ubiquitination by UBE2G2/GP78 appears to involve the transfer of preassembled Ub chains from UBE2G2 to lysine residues in a substrate. The E2 and E3 enzymes form a large hetero-oligomer which brings multiple UBE2G2 Molecules into close proximity which allows for Ub transfer between neighboring E2s.
Synonym: Ubiquitin-Conjugating Enzyme E2 G2, Ubiquitin Carrier Protein G2, Ubiquitin-Protein Ligase G2, UBE2G2
- Molecular Weight
- 45.0 kDa
- UniProt
- P60604
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