TNF Receptor II/TNF RII/TNFRSF1B/CD120b protein (Fc Tag)

Catalog No. ABIN7321038

This Recombinant TNF Receptor II/TNF RII/TNFRSF1B/CD120b protein is expressed in Human Cells.

Quick Overview for TNF Receptor II/TNF RII/TNFRSF1B/CD120b protein (Fc Tag) (ABIN7321038)

Target: TNF Receptor II/TNF RII/TNFRSF1B/CD120b

Protein Type: Recombinant

Origin: Rhesus Monkey

Source: Human Cells

Purity: >95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: Fc Tag

Purpose: Recombinant Rhesus Macaque TNF Receptor II/TNF RII/TNFRSF1B/CD120b (C-Fc)

Sequence: Leu23-Asp257

Characteristics: Recombinant Rhesus Macaque Tumor Necrosis Factor Receptor II is produced by our Mammalian expression system and the target gene encoding Leu23-Asp257 is expressed with a Fc tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Comment:

60-80 kDa

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: TNF Receptor II/TNF RII/TNFRSF1B/CD120b

Background:

Background: Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains: Tumor necrosis factor receptor superfamily member 1b and membrane form and Tumor necrosis factor-binding protein 2. TNFRSF1B is a receptor with high affinity for TNFSF2/TNF-α and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-α. TNFRSF1B mediates most of the metabolic effects of TNF-α. TNF-α-induced apoptosis suggests that it regulates TNF-α function by antagonizing its biological activity.

Synonym: TNF-RII, TNFRII, TNF RII, Tumor necrosis factor receptor superfamily member 1b, Tnfrsf1b

Molecular Weight: 52 kDa

UniProt: F7EAF8