TACSTD2 Protein (His tag)

Catalog No. ABIN7321045

This Recombinant TACSTD2 protein is produced in Human Cells.

Quick Overview for TACSTD2 Protein (His tag) (ABIN7321045)

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Protein Type: Recombinant

Biological Activity: Active

Origin: Rhesus Monkey

Source: Human Cells

Purity: >95 % as determined by reducing SDS-PAGE.

Product Details

Purification tag / Conjugate: This TACSTD2 protein is labelled with His tag.

Purpose: Recombinant Rhesus Macaque Tumor-associated Calcium Signal Transducer 2/TROP-2 (C-6His)

Sequence: His27-Arg272

Characteristics: Recombinant Rhesus Macaque Tumor-associated Calcium Signal Transducer 2 is produced by our Mammalian expression system and the target gene encoding His27-Arg272 is expressed with a 6His tag at the C-terminus.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Biological Activity Comment: Immobilized Rhesus Macaque TROP-2-His(Cat#PKSQ050121) at 2μg/ml (100 μl/well) can bind Anti-Human TROP-2 mAb .The ED50 of Anti-Human TROP-2 mAb is 4.7 ng/ml.

Application Details

Comment:

38-45 kDa

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Alternative Name: Tumor-associated Calcium Signal Transducer 2/TROP-2

Background:

Background: Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87 % amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.

Synonym: Tumor-associated calcium signal transducer 2, Membrane component chromosome 1 surfacemarker 1, Cell surface glycoprotein Trop-2, TACSTD2, TROP2

Molecular Weight: 28.7 kDa

NCBI Accession: XP_001114599