HCoV-OC43 N Protein

Catalog No. ABIN7198822

This Recombinant HCoV-OC43 N protein is expressed in Escherichia coli (E. coli).

Quick Overview for HCoV-OC43 N Protein (ABIN7198822)

Target: HCoV-OC43 N (Coronavirus OC43 Nucleoprotein (HCoV-OC43 N))

Protein Type: Recombinant

Origin: Human Coronavirus OC43 (HCoV-OC43)

Source: Escherichia coli (E. coli)

Purity: Greater than 90 % as determined by reducing SDS-PAGE.

Product Details

Purpose: Recombinant HCoV-OC43 Nucleocapsid Protein

Sequence: Met1-Ile448

Characteristics: Recombinant HCoV-OC43 Nucleocapsid Protein is produced by our E.coli expression system and the target gene encoding Met1-Ile448 is expressed with a 6His tag at the N-terminus.

Endotoxin Level: Please contact us for more information.

Biological Activity Comment: Test in progress

Application Details

Comment:

57kDa

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM NaAc-HAc, 150 mM NaCl, 5 % Trehalose, pH 4.5

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: HCoV-OC43 N (Coronavirus OC43 Nucleoprotein (HCoV-OC43 N))

Alternative Name: Coronavirus OC-43 Nucleoprotein

Background:

Background: Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

Synonym: HCoV-OC43 Nucleocapsid Protein, HCoV-OC43 coronavirus NP Protein, HCoV-OC43 np Protein, HCoV-OC43 novel coronavirus Nucleoprotein Protein

Molecular Weight: 53kDa     

UniProt: P33469