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CD38 Protein (Biotin,His-Avi Tag)

This Recombinant CD38 protein is expressed in Human Cells.
Catalog No. ABIN7319793

Quick Overview for CD38 Protein (Biotin,His-Avi Tag) (ABIN7319793)

Target

See all CD38 Proteins
CD38

Protein Type

Recombinant

Origin

  • 21
  • 9
  • 5
  • 4
  • 1
Human

Source

  • 15
  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human Cells

Purity

>95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CD38 protein is labelled with Biotin,His-Avi Tag.

    Purpose

    Recombinant Human ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1/CD38 (N-6His-Avi) Biotinylated

    Sequence

    Val43-Ile300

    Characteristics

    Biotinylated Recombinant Human ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1 is produced by our Mammalian expression system and the target gene encoding Val43-Ile300 is expressed with a 6His, Avi tag at the N-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Comment

    40-50 kDa

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD38

    Background

    Background: CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a Signal-anchor for type II membrane protein. CD38 is able to transform NAD+ to ADP-D-ribose and nicotinamide. It also can transform NADP+ to nicotinate-adenine dinucleotide phosphate and nicotinamide. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

    Synonym: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1 

    Molecular Weight

    33.3 kDa

    UniProt

    P28907
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