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CD52 Protein (CD52) (Biotin)

This Recombinant CD52 protein is produced in Human Cells.
Catalog No. ABIN7319777

Quick Overview for CD52 Protein (CD52) (Biotin) (ABIN7319777)

Target

See all CD52 Proteins
CD52

Protein Type

Recombinant

Origin

  • 12
  • 1
Human

Source

  • 8
  • 3
  • 1
  • 1
Human Cells

Purity

>95 % as determined by reducing SDS-PAGE.
  • Purification tag / Conjugate

    This CD52 protein is labelled with Biotin.

    Purpose

    Recombinant Human CD52 (C-Fc-Avi) Biotinylated

    Sequence

    Gly25-Ser36

    Characteristics

    Biotinylated Recombinant Human CAMPATH-1 Antigen is produced by our Mammalian expression system and the target gene encoding Gly25-Ser36 is expressed with a Fc, Avi tag at the C-terminus.

    Endotoxin Level

    < 1.0 EU per μg as determined by the LAL method.
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  • Comment

    38-50 kDa

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Storage

    4 °C,-20 °C,-80 °C

    Storage Comment

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    CD52

    Alternative Name

    CD52

    Background

    Background: CD52, also known as CAMPATH-1 antigen, HE5, and gp20, is a cell surface glycoprotein that can be targeted to induce immune suppression by complement-mediated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocycte-derived dendritic cells, eosinophils, and neutrophils, as well as on mature spermatozoa and epithelial cells lining the male genital tract. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.

    Synonym: CAMPATH-1 antigen, CAMPATH-1, CD52 antigen, CD52 Molecule, CD52,  CDw52, Epididymal secretory protein E5, He5, HEL-S-171mP, Human epididymis-specific protein 5

    Molecular Weight

    30.2 kDa

    UniProt

    P31358
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