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CD52 Protein (CD52) (Fc Tag,AVI tag)

CD52 Origin: Human Host: HEK-293 Cells Recombinant > 95 % by SDS-PAGE. Active
Catalog No. ABIN7519800
  • Target See all CD52 Proteins
    CD52
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 10
    • 2
    Human
    Source
    • 8
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD52 protein is labelled with Fc Tag,AVI tag.
    Purpose
    Active Recombinant Human CD52 Protein
    Sequence
    GQNDTSQTSS PS
    Specificity
    Gly25-Ser36
    Purity
    > 95 % by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    <0.1EU/μg
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Human CD52 Protein at 5 μg/mL (100 μL/well) can bind SIGLEC10 with a linear range of 20.49-455.65ng/mL.
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    Discover our top product CD52 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    Buffer
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • Target
    CD52
    Alternative Name
    CD52 (CD52 Products)
    Synonyms
    CD52 Protein, AI463198 Protein, B7 Protein, B7-Ag Protein, CAMPATH-1 Protein, CLS1 Protein, MB7 Protein, CDW52 Protein, CE5 Protein, CD52 molecule Protein, CD52 antigen Protein, CD52 Protein, Cd52 Protein
    Background

    Description: CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.

    Name: CD52,CDW52,EDDM5

    Gene ID
    1043
    UniProt
    P31358
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