Recombinant Human IgG3 Isotype Control

Catalog No. ABIN7211743

Quick Overview for Recombinant Human IgG3 Isotype Control (ABIN7211743)

Target: IgG3

Antibody Type: Recombinant Antibody

Application: Isotype Control (IsoC), In vivo Studies (in vivo)

Grade: In vivo Grade

Isotype: IgG3

Product Details

Reactivity: Human

Host: Human

Expression System: Mammalian cells

Purpose: In Vivo Grade Recombinant Human IgG3 Fc Protein

Specificity: The recombinant human IgG3 Fc protein (hIgG3 Fc) includes the CH2 and CH3 domains of the heavy chain constant region. Most of the therapeutic antibody drugs and Fc fusion proteins carry the natural human IgG3 Fc region or engineered mutants.

Characteristics: The recombinant human IgG3 Fc protein (hIgG3 Fc) includes the CH2 and CH3 domains of the heavy chain constant region. Most of the therapeutic antibody drugs and Fc fusion proteins carry the natural human IgG3 Fc region or engineered mutants. The recombinant human IgG3 Fc protein can be used as the isotype control of the hIgG3 antibodies and the hIgG3 Fc fusion proteins in various in vitro and in vivo experiments. Recombinant natural and engineered human IgG3 Fc proteins, and recombinant human IgG3 isotype control antibody and mutants are available. Biotinylated hIgG3 Fc, and hIgG3 Fc with Avi-, His-, and Flag-tags are also available. Please contact us to ask for a quote for the engineered human IgG3 Fc proteins, biotinylated hIgG3 Fc, and hIgG3 Fc with Avi-, His-, and Flag-tags.

Purification: Protein A or G affinity column

Purity: >95 % by SDS-PAGE under reducing conditions

Sterility: Sterile filtered

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Application Details

Application Notes: The recombinant human IgG3 Fc protein can be used as the isotype control of the hIgG3 antibodies and the hIgG3 Fc fusion proteins in various in vitro and in vivo experiments.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4

Storage: 4°C,-20 °C

Storage Comment: 1 month from date of receipt, 2 to 8°C as supplied. 3 months from date of receipt, -20°C to -70°C as supplied.

Expiry Date: 3 months

Target Details

Target: IgG3

Target Type: Antibody

Molecular Weight: Predicted 26.1 kDa. Due to glycosylation, the recombinant human IgG3 Fc protein migrates to 32-34 kDa based on the Bis-Tris PAGE result.