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alpha Fetoprotein Protein (AA 19-609) (His tag)

Recombinant alpha Fetoprotein protein expressed in HEK-293 Cells.
Catalog No. ABIN7273808
$445.92
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Quick Overview for alpha Fetoprotein Protein (AA 19-609) (His tag) (ABIN7273808)

Target

See all alpha Fetoprotein (AFP) Proteins
alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 14
  • 9
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Cynomolgus

Source

  • 21
  • 9
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 19-609

    Purification tag / Conjugate

    This alpha Fetoprotein protein is labelled with His tag.

    Purpose

    Cynomolgus AFP Protein

    Sequence

    Arg19-Val609

    Characteristics

    Recombinant Cynomolgus AFP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg19-Val609.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Cynomolgus AFP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Cynomolgus AFP is greater than 95% as determined by SEC-HPLC.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

    Alternative Name

    AFP

    Background

    Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases.

    Molecular Weight

    67.53 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result.

    UniProt

    A0A2K5U7U0

    Pathways

    C21-Steroid Hormone Metabolic Process
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