alpha Fetoprotein Protein (AA 19-609) (His tag)
Quick Overview for alpha Fetoprotein Protein (AA 19-609) (His tag) (ABIN7273808)
Target
See all alpha Fetoprotein (AFP) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 19-609
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Purification tag / Conjugate
- This alpha Fetoprotein protein is labelled with His tag.
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Purpose
- Cynomolgus AFP Protein
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Sequence
- Arg19-Val609
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Characteristics
- Recombinant Cynomolgus AFP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg19-Val609.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Cynomolgus AFP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Cynomolgus AFP is greater than 95% as determined by SEC-HPLC.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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Alternative Name
- AFP
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Background
- Alpha-fetoprotein is a shuttle protein that delivers nutrients through receptor-mediated endocytosis to embryotic cells. In adults, alpha-fetoprotein can shuttle drugs into alpha-fetoprotein receptor-positive myeloid-derived suppressor, regenerating and also cancer cells. Drugs with high-binding affinity to alpha-fetoprotein can activate or deplete targeted cells. Myeloid-derived suppressor cells activation leads to immune suppression that can be used for treating autoimmune diseases.
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Molecular Weight
- 67.53 kDa. Due to glycosylation, the protein migrates to 68-75 kDa based on Bis-Tris PAGE result.
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UniProt
- A0A2K5U7U0
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Pathways
- C21-Steroid Hormone Metabolic Process
Target
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