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Aspartate beta Hydroxylase Protein (AA 341-758) (His tag)

This Recombinant Aspartate beta Hydroxylase protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN7273878
$388.17
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Quick Overview for Aspartate beta Hydroxylase Protein (AA 341-758) (His tag) (ABIN7273878)

Target

See all Aspartate beta Hydroxylase (ASPH) Proteins
Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 15
  • 3
Human

Source

  • 7
  • 7
  • 2
  • 2
Escherichia coli (E. coli)

Purity

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 341-758

    Purification tag / Conjugate

    This Aspartate beta Hydroxylase protein is labelled with His tag.

    Purpose

    Human ASPH Protein

    Sequence

    Ile341-Ile758

    Characteristics

    Recombinant Human ASPH Protein is expressed from E.coli with His tag at the N-Terminus.It contains Ile341-Ile758.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1 EU per ug by the LAL method.

    Biological Activity Comment

    Human ASPH on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human ASPH is greater than 95% as determined by SEC-HPLC.
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl ( pH 7.4).

    Storage

    -80 °C

    Storage Comment

    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

    Alternative Name

    ASPH

    Background

    Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication.Expression profiling of Notch signaling components positively correlates with ASPH expression in breast cancer patients, confirming that ASPH-Notch axis acts functionally in breast tumorigenesis.

    Molecular Weight

    49.2 kDa same as Bis-Tris PAGE result.

    UniProt

    Q12797

    Pathways

    Positive Regulation of Endopeptidase Activity
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