IREM1 Protein (AA 20-156) (hFc Tag)

Catalog No. ABIN7274155

This Recombinant IREM1 protein is expressed in HEK-293 Cells.

Quick Overview for IREM1 Protein (AA 20-156) (hFc Tag) (ABIN7274155)

Target: IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 20-156

Purification tag / Conjugate: This IREM1 protein is labelled with hFc Tag.

Purpose: Human CD300LF Protein

Sequence: Thr20-Ser156

Characteristics: Recombinant Human CD300LF Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Thr20-Ser156.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Human CD300LF on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human CD300LF is greater than 95% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: IREM1 (Immune Receptor Expressed On Myeloid Cells 1 (IREM1))

Alternative Name: CD300LF

Background: Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. CD300lf as a proteinaceous receptor for MNoV. Interestingly, its paralogue CD300ld was also sufficient for MNoV infection in vitro. CD300lf is essential for both oral and parenteral MNoV infection and to elicit anti-MNoV humoral responses in vivo. human CD300lf (huCD300lf) is not essential for HNoV infection, nor does huCD300lf inhibit binding of HNoV virus-like particles to glycans.

Molecular Weight: 42.1 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

UniProt: Q8TDQ1