CD46 Protein (CD46) (AA 45-344) (His tag)
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- Target See all CD46 Proteins
- CD46
- Protein Type
- Recombinant
- Protein Characteristics
- AA 45-344
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Origin
- Dog
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD46 protein is labelled with His tag.
- Purpose
- Canine CD46 Protein
- Sequence
- Cys45-Gly344
- Characteristics
- Recombinant Canine CD46 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys45-Gly344.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product CD46 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CD46
- Alternative Name
- CD46 (CD46 Products)
- Background
- CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.
- Molecular Weight
- 34.11 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A8C0YZN5
- Pathways
- Regulation of Actin Filament Polymerization
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