IL17RA Protein (AA 32-322) (Fc Tag)
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- Target See all IL17RA Proteins
- IL17RA (Interleukin 17 Receptor A (IL17RA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-322
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL17RA protein is labelled with Fc Tag.
- Purpose
- Mouse IL-17R alpha/CD217 Protein
- Sequence
- Ser32-Trp322
- Characteristics
- Recombinant Mouse IL-17R alpha/CD217 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser32-Trp322.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Mouse IL-17A&F, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 19.8ng/ml determined by ELISA. See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IL17RA (Interleukin 17 Receptor A (IL17RA))
- Alternative Name
- IL-17R alpha (IL17RA Products)
- Background
- Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 R) which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL-17 R gene was localized to chromosome 22.
- Molecular Weight
- 60.1 kDa. Due to glycosylation, the protein migrates to 95-110 kDa based on Tris-Bis PAGE result.
- UniProt
- Q60943
- Pathways
- SARS-CoV-2 Protein Interactome
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