LI Cadherin Protein (AA 23-787) (FITC,His tag)
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- Target See all LI Cadherin Proteins
- LI Cadherin
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-787
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LI Cadherin protein is labelled with FITC,His tag.
- Purpose
- FITC-Labeled Human CDH17/Cadherin 17 Protein
- Sequence
- Gln23-Met787
- Characteristics
- Recombinant FITC-Labeled Human CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Met787.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product LI Cadherin Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LI Cadherin
- Alternative Name
- CDH17 (LI Cadherin Products)
- Synonyms
- CDH16 Protein, HPT-1 Protein, HPT1 Protein, HPT-1/LI Protein, cb903 Protein, fb65d02 Protein, wu:fb65d02 Protein, cadherin-17 Protein, cadherin 17 Protein, cadherin 17, LI cadherin (liver-intestine) Protein, CDH17 Protein, Cdh17 Protein, cdh17 Protein
- Background
- Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
- Molecular Weight
- 86.1 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Tris-Bis PAGE result.
- UniProt
- Q12864
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