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LI Cadherin Protein (AA 23-787) (His tag,FITC)

This Recombinant LI Cadherin protein is produced in HEK-293 Cells.
Catalog No. ABIN7274307
$1,196.67
Plus shipping costs $50.00, if applicable $20.00 dry ice
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Quick Overview for LI Cadherin Protein (AA 23-787) (His tag,FITC) (ABIN7274307)

Target

See all LI Cadherin Proteins
LI Cadherin

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 31
  • 5
  • 3
  • 2
  • 1
  • 1
Human

Source

  • 29
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Bis-Tris PAGE
  • Protein Characteristics

    AA 23-787

    Purification tag / Conjugate

    This LI Cadherin protein is labelled with His tag,FITC.

    Purpose

    FITC-Labeled Human CDH17/Cadherin 17 Protein

    Sequence

    Gln23-Met787

    Characteristics

    Recombinant FITC-Labeled Human CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Met787.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized FITC-Labeled Human CDH17, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA.,FITC-Labeled Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).

    Storage

    -80 °C

    Storage Comment

    Valid for 6 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    6 months
  • Target

    LI Cadherin

    Alternative Name

    CDH17

    Background

    Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

    Molecular Weight

    86.1 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Bis-Tris PAGE result.

    UniProt

    Q12864
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