LI Cadherin Protein (AA 23-787) (His tag,FITC)
Quick Overview for LI Cadherin Protein (AA 23-787) (His tag,FITC) (ABIN7274307)
Target
See all LI Cadherin ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 23-787
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Purification tag / Conjugate
- This LI Cadherin protein is labelled with His tag,FITC.
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Purpose
- FITC-Labeled Human CDH17/Cadherin 17 Protein
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Sequence
- Gln23-Met787
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Characteristics
- Recombinant FITC-Labeled Human CDH17/Cadherin 17 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln23-Met787.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized FITC-Labeled Human CDH17, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA.,FITC-Labeled Human CDH17 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 6 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 6 months
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- LI Cadherin
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Alternative Name
- CDH17
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Background
- Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
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Molecular Weight
- 86.1 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Bis-Tris PAGE result.
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UniProt
- Q12864
Target
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