LI Cadherin Protein (AA 30-244) (His tag)
Quick Overview for LI Cadherin Protein (AA 30-244) (His tag) (ABIN7274310)
Target
See all LI Cadherin ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 30-244
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Purification tag / Conjugate
- This LI Cadherin protein is labelled with His tag.
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Purpose
- Human CDH17/Cadherin 17 Domain 1&2 Protein
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Sequence
- Pro30-Pro244
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Characteristics
- Recombinant Human CDH17/Cadherin 17 Domain 1&2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro30-Pro244.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human CDH17 Domain 1&2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CDH17 Antibody, hFc Tag with the EC50 of 4.7ng/ml determined by ELISA (QC Test).,Human CDH17 Domain 1&2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,Loaded Anti-CDH17 Ab., hFc-Avi Tag on ProA-Biosensor can bind Human CDH17 Domain 1&2, His Tag with an affinity constant of 1.51 nM as determined in BLI assay (Gator® Prime).
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LI Cadherin (AA 23-787) (Active) protein (hFc Tag)
Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
LI Cadherin (AA 23-787) (Active) protein (Biotin,His-Avi Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
LI Cadherin (AA 1-795) protein (His tag)Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
LI Cadherin (AA 23-667) (Active) protein (His tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
LI Cadherin (AA 567-777) (Active) protein (hFc Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
LI Cadherin (AA 23-787) (Active) protein (His tag,FITC)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
LI Cadherin (AA 26-786) protein (His tag)Origin: Mouse Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
LI Cadherin (AA 567-667) protein (mFc Tag)Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
LI Cadherin (AA 567-667) protein (Fc Tag)Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
LI Cadherin (AA 24-131) protein (GST tag)Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- LI Cadherin
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Alternative Name
- CDH17
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Background
- Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
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Molecular Weight
- 25.15 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
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UniProt
- Q12864
Target
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