CADM3 Protein (AA 23-328) (His tag)

Catalog No. ABIN7274329

This Recombinant CADM3 protein is expressed in HEK-293 Cells.

Quick Overview for CADM3 Protein (AA 23-328) (His tag) (ABIN7274329)

Target: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 23-328

Purification tag / Conjugate: This CADM3 protein is labelled with His tag.

Purpose: Mouse CADM3 Protein

Sequence: Asn23-His328

Characteristics: Recombinant Mouse CADM3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asn23-His328.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Mouse CADM3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse CADM3 is greater than 95% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: CADM3 (Cell Adhesion Molecule 3 (CADM3))

Alternative Name: CADM3

Background: Cell adhesion molecules belonging to the Cadm family, and in particular Cadm3 (axonal) and its heterophilic binding partner Cadm4 (Schwann cell), mediate these interactions along the internode.over-expressing Cadm3 on the surface of DRG neuron axons results in an almost complete inability by Schwann cells to form myelin segments. Axons of superior cervical ganglion (SCG) neurons, which do not normally support the formation of myelin segments by Schwann cells, express higher levels of Cadm3 compared to DRG neurons.

Molecular Weight: 34.5 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.

UniProt: Q99N28

Pathways: Cell-Cell Junction Organization