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CLEC1A Protein (AA 73-269) (Fc Tag)

CLEC1A Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7274363
  • Target See all CLEC1A Proteins
    CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 73-269
    Origin
    • 6
    • 2
    • 1
    Mouse
    Source
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CLEC1A protein is labelled with Fc Tag.
    Purpose
    Mouse CLEC-1 Protein
    Sequence
    Gln73-Gln269
    Characteristics
    Recombinant Mouse CLEC-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Gln73-Gln269.
    Purity
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product CLEC1A Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CLEC1A (C-Type Lectin Domain Family 1, Member A (CLEC1A))
    Alternative Name
    CLEC-1 (CLEC1A Products)
    Synonyms
    RGD1566110 Protein, CLEC1 Protein, 5930406N14Rik Protein, C-type lectin domain family 1, member A Protein, C-type lectin domain family 1 member A Protein, C-type lectin domain family 1, member a Protein, Clec1a Protein, CLEC1A Protein
    Background
    C-type lectin-like receptor-1 (CLEC-1) is a member of the Dectin-1 cluster of pattern recognition receptors (PRRs). It is involved in host immunity, has immunoregulatory function, and supports allograft tolerance. CLEC-1 may act as a negative regulator of Dectin-1 induced host inflammatory response via suppressing neutrophils recruitment and production of pro-inflammatory cytokine IL-1β production in response to A. fumigatus keratitis.
    Molecular Weight
    50.4 kDa. Due to glycosylation, the protein migrates to 66-68 kDa based on Tris-Bis PAGE result.
    UniProt
    Q8BWY2
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