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CXCL13 Protein (AA 22-109) (hFc Tag)

Recombinant CXCL13 protein expressed in HEK-293 Cells.
Catalog No. ABIN7274450
$426.67
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Quick Overview for CXCL13 Protein (AA 22-109) (hFc Tag) (ABIN7274450)

Target

See all CXCL13 Proteins
CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 13
  • 4
  • 3
  • 1
  • 1
Mouse

Source

  • 16
  • 3
  • 2
HEK-293 Cells

Purity

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 22-109

    Purification tag / Conjugate

    This CXCL13 protein is labelled with hFc Tag.

    Purpose

    Mouse CXCL13/BCA-1 Protein

    Sequence

    Ile22-Ala109

    Characteristics

    Recombinant Mouse CXCL13/BCA-1 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Ile22-Ala109.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Mouse CXCL13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse CXCL13 is greater than 95% as determined by SEC-HPLC.
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Supplied as 0.22μm filtered solution in 50 mM Tris, 500 mM NaCl ( pH 7.5).

    Storage

    -80 °C

    Storage Comment

    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

    Alternative Name

    CXCL13

    Background

    Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.

    Molecular Weight

    37.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

    UniProt

    O55038
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