CXCL13 Protein (AA 22-109) (hFc Tag)
Quick Overview for CXCL13 Protein (AA 22-109) (hFc Tag) (ABIN7274450)
Target
See all CXCL13 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 22-109
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Purification tag / Conjugate
- This CXCL13 protein is labelled with hFc Tag.
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Purpose
- Mouse CXCL13/BCA-1 Protein
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Sequence
- Ile22-Ala109
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Characteristics
- Recombinant Mouse CXCL13/BCA-1 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-Terminus.It contains Ile22-Ala109.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Mouse CXCL13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse CXCL13 is greater than 95% as determined by SEC-HPLC.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in 50 mM Tris, 500 mM NaCl ( pH 7.5).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
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Alternative Name
- CXCL13
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Background
- Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
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Molecular Weight
- 37.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
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UniProt
- O55038
Target
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