CXCL16 Protein (AA 27-201) (hFc Tag)

Catalog No. ABIN7274451

This Recombinant CXCL16 protein is produced in HEK-293 Cells.

Quick Overview for CXCL16 Protein (AA 27-201) (hFc Tag) (ABIN7274451)

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC

Product Details

Protein Characteristics: AA 27-201

Purification tag / Conjugate: This CXCL16 protein is labelled with hFc Tag.

Purpose: Mouse CXCL16 Protein

Sequence: Asn27-Trp201

Characteristics: Recombinant Mouse CXCL16 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Asn27-Trp201.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Mouse CXCL16 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse CXCL16 is greater than 90% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Alternative Name: CXCL16

Background: CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall cells, leukocytes and platelets express and/or release CXCL16 under the regulation of inflammatory mediators. CXCL16 expression is increased in experimental and human nephropathies. Targeting CXCL16 protected from experimental glomerular injury or interstitial fibrosis.

Molecular Weight: 45.9 kDa. Due to glycosylation, the protein migrates to 68-70 kDa based on Bis-Tris PAGE result.

UniProt: Q8BSU2