DR3/LARD Protein (AA 31-196) (His tag)
Quick Overview for DR3/LARD Protein (AA 31-196) (His tag) (ABIN7274495)
Target
See all DR3/LARD (TNFRSF25) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 31-196
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Purification tag / Conjugate
- This DR3/LARD protein is labelled with His tag.
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Purpose
- Mouse DR3/TNFRSF25 Protein
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Sequence
- Gln31-Met196
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Characteristics
- Recombinant Mouse DR3/TNFRSF25 Protein is expressed from HEK293 with His tag at the C-Terminus., It contains Gln31-Met196.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
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Alternative Name
- DR3
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Background
- TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly express DR3.
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Molecular Weight
- 18.79 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.
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UniProt
- B1AWN9
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Pathways
- Apoptosis
Target
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