Ephrin B2 Protein (EFNB2) (AA 28-229) (Fc Tag)
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- Target See all Ephrin B2 (EFNB2) Proteins
- Ephrin B2 (EFNB2)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-229
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Ephrin B2 protein is labelled with Fc Tag.
- Purpose
- Human Ephrin-B2/EFNB2 Protein
- Sequence
- Ile28-Ala229
- Characteristics
- Recombinant Human Ephrin-B2/EFNB2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile28-Ala229.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Ephrin B2 (EFNB2) (AA 28-127) protein (GST tag)
EFNB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Ephrin B2 (EFNB2) protein (His tag,Fc Tag)EFNB2 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Ephrin B2 (EFNB2) (AA 1-333) protein (GST tag)EFNB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Ephrin B2 (EFNB2)
- Alternative Name
- Ephrin-B2 (EFNB2 Products)
- Background
- Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 is an important regulator of PDGFRβ endocytosis and thereby acts as a molecular switch controlling the downstream signaling activity of this receptor in mural cells.
- Molecular Weight
- 49 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_004084
- Pathways
- RTK Signaling, Regulation of Muscle Cell Differentiation
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