FAS Protein (AA 26-173) (His tag)
-
- Target See all FAS Proteins
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-173
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FAS protein is labelled with His tag.
- Purpose
- Human Fas/TNFRSF6/CD95 Protein
- Sequence
- Gln26-Asn173
- Characteristics
- Recombinant Human Fas/TNFRSF6/CD95 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln26-Asn173.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 19.45 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product FAS Protein
-
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) protein (Fc Tag)
FAS Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TNF Receptor Superfamily, Member 6 (FAS) (AA 22-169) protein (Fc Tag)FAS Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
TNF Receptor Superfamily, Member 6 (FAS) (AA 25-169) protein (His-DYKDDDDK-Strep II Tag)FAS Origin: Human Host: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
TNF Receptor Superfamily, Member 6 (FAS) protein (His tag)FAS Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
TNF Receptor Superfamily, Member 6 (FAS) (AA 17-173) protein (His tag)FAS Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) protein (GST tag)FAS Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) (Active) protein (His tag)FAS Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS, AcA Active
TNF Receptor Superfamily, Member 6 (FAS) (Active) protein (His tag)FAS Origin: Mouse Host: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
TNF Receptor Superfamily, Member 6 (FAS) (Active) protein (His tag)FAS Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) (Active) protein (Fc Tag)FAS Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Alternative Name
- Fas (FAS Products)
- Background
- CD95 (also known as Fas) is a member of the tumor necrosis factor receptor (TNFR) superfamily. Its cognate ligand, CD95L, is implicated in immune homeostasis and immune surveillance. Mutations in this receptor are associated with a loss of apoptotic signaling and have been detected in an autoimmune disorder called autoimmune lymphoproliferative syndrome (ALPS) type Ia, which shares some clinical features with systemic lupus erythematosus (SLE).
- Molecular Weight
- 13.7 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
- UniProt
- P25445-1
- Pathways
- p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
-
