Factor XI Protein (AA 19-625) (His tag)
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- Target See all Factor XI (F11) Proteins
- Factor XI (F11) (Coagulation Factor XI (F11))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-625
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Factor XI protein is labelled with His tag.
- Purpose
- Human Coagulation factor XI Protein
- Sequence
- Glu19-Val625
- Characteristics
- Recombinant Human Coagulation factor XI Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu19-Val625.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Coagulation Factor XI (F11) (AA 1-625) protein (GST tag)
F11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor XI (F11) (AA 286-385) protein (GST tag)F11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor XI (F11) (AA 19-387) protein (His tag)Crystallography grade F11 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor XI (F11) (AA 388-625) protein (His tag)Crystallography grade F11 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor XI (F11) (AA 19-389) protein (His tag)Crystallography grade F11 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor XI (F11) (AA 390-624) protein (His tag)Crystallography grade F11 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in 25 mM HEPES, 150 mM NaCl ( pH 7.5). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Factor XI (F11) (Coagulation Factor XI (F11))
- Alternative Name
- Coagulation factor XI (F11 Products)
- Synonyms
- FXI Protein, 1600027G01Rik Protein, AI503996 Protein, Cf11 Protein, LRRGT00086 Protein, coagulation factor XI Protein, F11 Protein, CpipJ_CPIJ000593 Protein, CpipJ_CPIJ001060 Protein, CpipJ_CPIJ002752 Protein, CpipJ_CPIJ003631 Protein, CpipJ_CPIJ004041 Protein, CpipJ_CPIJ004093 Protein
- Background
- Coagulation factor (F)XI has been described as a component of the early phase of the contact pathway of blood coagulation, acting downstream of factor XII.In contrast to its mild hemostatic activities, FXI is known to play a significant role in thrombosis, as it is a demonstrated independent risk factor for deep vein thrombosis, ischemic stroke, and myocardial infarction. A better understanding of the varied and complex role of FXI in both thrombosis and hemostasis will help to allow better prediction of bleeding risk in FXI-deficient patients and also informing the development of targeted agents to inhibit the thrombotic activities of FXI while preserving hemostasis.
- Molecular Weight
- 69.1 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
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