GAS6 Protein (AA 49-678) (His tag)
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- Target See all GAS6 Proteins
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 49-678
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GAS6 protein is labelled with His tag.
- Purpose
- Human GAS6 Protein
- Sequence
- Ala49-Ala678
- Characteristics
- Recombinant Human GAS6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala49-Ala678.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human GAS6, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Anti-GAS6 Antibody, hFc Tag with the EC50 of 11.7ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product GAS6 Protein
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Growth Arrest-Specific 6 (GAS6) (AA 31-637) protein (His tag)
GAS6 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Arrest-Specific 6 (GAS6) (Active) protein (His tag)GAS6 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
Growth Arrest-Specific 6 (GAS6) (AA 31-678) protein (His tag)GAS6 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Growth Arrest-Specific 6 (GAS6) (AA 1-678) protein (GST tag)GAS6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Arrest-Specific 6 (GAS6) (AA 136-311) (Active) protein (His tag)GAS6 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Alternative Name
- GAS6 (GAS6 Products)
- Background
- Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
- Molecular Weight
- 70.60 kDa. Due to glycosylation, the protein migrates to 71-75 kDa based on Tris-Bis PAGE result.
- Pathways
- RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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