GAS6 Protein (His tag)
-
- Target See all GAS6 Proteins
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Human Cells
- Purification tag / Conjugate
- This GAS6 protein is labelled with His tag.
- Purpose
- Recombinant Human GAS6 (C-6His)
- Sequence
- Ala31-Ala678
- Characteristics
- Recombinant Human Growth Arrest-specific Protein 6 is produced by our Mammalian expression system and the target gene encoding Ala31-Ala678 is expressed with a 6His tag at the C-terminus.
- Purity
- >95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human AXL-His (Cat#C02B) at 10μg/ml (100 μl/well) can bind Human GAS6-His* (Cat#C01W).*: Biotinylated by NHS-biotin prior to testing.The ED50 of Recombinant Human GAS6-His* (Cat#C01W) is 0.04466 ug/ml.
- Top Product
- Discover our top product GAS6 Protein
-
Growth Arrest-Specific 6 (GAS6) (AA 31-637) protein (His tag)
GAS6 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Arrest-Specific 6 (GAS6) (AA 49-678) protein (His tag)GAS6 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Growth Arrest-Specific 6 (GAS6) (AA 1-678) protein (GST tag)GAS6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Arrest-Specific 6 (GAS6) (AA 579-678) protein (GST tag)GAS6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Arrest-Specific 6 (GAS6) (AA 31-721) protein (His tag)Crystallography grade GAS6 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Arrest-Specific 6 (GAS6) (AA 28-674) protein (His tag)Crystallography grade GAS6 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Arrest-Specific 6 (GAS6) (AA 136-311) (Active) protein (His tag)GAS6 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
-
- Restrictions
- For Research Use only
-
- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of PBS, 10 % Glycerol, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- Target
- GAS6 (Growth Arrest-Specific 6 (GAS6))
- Alternative Name
- GAS6 (GAS6 Products)
- Synonyms
- fj34a12 Protein, zgc:63860 Protein, wu:fj34a12 Protein, MGC68463 Protein, gas6 Protein, MGC83872 Protein, GAS6 Protein, Gas-6 Protein, AXLLG Protein, AXSF Protein, growth arrest specific 6 Protein, growth arrest-specific 6 Protein, growth arrest specific 6 L homeolog Protein, growth arrest specific 6 S homeolog Protein, GAS6 Protein, gas6 Protein, gas6.L Protein, gas6.S Protein, Gas6 Protein
- Background
-
Background: GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Synonym: AXLLG, AXLLGAXL stimulatory factor, AXSFAXL receptor tyrosine kinase ligand, Gas6, GAS-6, growth arrest-specific 6, growth arrest-specific protein 6
- Molecular Weight
- 72.7 kDa
- UniProt
- Q14393
- Pathways
- RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
-
