CD235a/GYPA Protein (AA 20-91) (His tag)
Quick Overview for CD235a/GYPA Protein (AA 20-91) (His tag) (ABIN7274763)
Target
See all CD235a/GYPA (GYPA) ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 20-91
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Purification tag / Conjugate
- This CD235a/GYPA protein is labelled with His tag.
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Purpose
- Cynomolgus GPA Protein
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Sequence
- Ser20-Glu91
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Characteristics
- Recombinant Cynomolgus GPA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser20-Glu91.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Cynomolgus GPA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Cynomolgus GPA is greater than 95% as determined by SEC-HPLC.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
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Alternative Name
- GPA
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Background
- Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes the rapidly progressive disorder one of the most challenging dilemmas in clinical medicine.The ultimate goal is an improved prognosis through outcome measures which assesses the disease control with minimal adverse effects of intensive immunosuppressive regimens, an integral part of the clinical approach to improve the quality of life of GPA patients.
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Molecular Weight
- 9 kDa. Due to glycosylation, the protein migrates to 30-45 kDa based on Bis-Tris PAGE result.
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UniProt
- A0A2K5WD82
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Pathways
- Maintenance of Protein Location
Target
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