IL1A Protein (AA 113-271) (His tag)
Quick Overview for IL1A Protein (AA 113-271) (His tag) (ABIN7274874)
Target
See all IL1A ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 113-271
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Purification tag / Conjugate
- This IL1A protein is labelled with His tag.
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Purpose
- Cynomolgus IL-1 alpha/IL-1A Protein
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Sequence
- Ser113-Ala271
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Characteristics
- Recombinant Cynomolgus IL-1 alpha/IL-1A Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser113-Ala271.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- IL1A (Interleukin 1 alpha (IL1A))
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Alternative Name
- IL-1 alpha
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Background
- The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
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Molecular Weight
- 19.23 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
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UniProt
- P79340
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Pathways
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
Target
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