LAMP5 Protein (AA 30-235) (His tag)

Catalog No. ABIN7275123

This Recombinant LAMP5 protein is produced in HEK-293 Cells.

Quick Overview for LAMP5 Protein (AA 30-235) (His tag) (ABIN7275123)

Target: LAMP5 (Lysosomal-Associated Membrane Protein Family, Member 5 (LAMP5))

Protein Type: Recombinant

Biological Activity: Active

Origin: Cynomolgus

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 30-235

Purification tag / Conjugate: This LAMP5 protein is labelled with His tag.

Purpose: Cynomolgus LAMP5 Protein

Sequence: Glu30-Glu235

Characteristics: Recombinant Cynomolgus LAMP5 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu30-Glu235.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Cynomolgus LAMP5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Cynomolgus LAMP5 is greater than 95% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: LAMP5 (Lysosomal-Associated Membrane Protein Family, Member 5 (LAMP5))

Alternative Name: LAMP5

Background: Lysosome-associated membrane protein 5 (LAMP5) is a mammalian ortholog of the Caenorhabditis elegans protein, UNC-46, which functions as a sorting factor to localize the vesicular GABA transporter UNC-47 to synaptic vesicles. In the mouse forebrain, LAMP5 is expressed in a subpopulation of GABAergic neurons in the olfactory bulb and the striato-nigral system, where it is required for fine-tuning of GABAergic synaptic transmission.

Molecular Weight: 24.17 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.

UniProt: G7PGY6