LILRB5 Protein (AA 18-456) (His-Avi Tag)
Quick Overview for LILRB5 Protein (AA 18-456) (His-Avi Tag) (ABIN7275193)
Target
See all LILRB5 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 18-456
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Purification tag / Conjugate
- This LILRB5 protein is labelled with His-Avi Tag.
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Purpose
- Non-biotinylated Human LILRB5/CD85c/LIR-8 Protein
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Sequence
- Arg18-His456
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Characteristics
- Recombinant Human LILRB5/CD85c/LIR-8 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Arg18-His456.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Human LILRB5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human LILRB5 is greater than 95% as determined by SEC-HPLC.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- LILRB5 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 5 (LILRB5))
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Alternative Name
- LILRB5
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Background
- LILRB5, also known as CD85c andLIR-8, belongs to a family of transmembrane glycoproteins that negatively regulate immune cell activation. Mature human LIR-8 consists of a 435 amino acid (aa) extracellular domain with four Ig-like domains, a 21 aa transmembrane segment, and a 111 aa cytoplasmic domain with two immunoreceptor tyrosine-based inhibitory motifs (ITIM). LILRB5 may act as receptor for class I MHC antigens.
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Molecular Weight
- 49.9 kDa. Due to glycosylation, the protein migrates to 67-72 kDa based on Bis-Tris PAGE result.
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UniProt
- O75023
Target
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