MANSC1 Protein (AA 25-369) (His tag)

Catalog No. ABIN7275228

This Recombinant MANSC1 protein is produced in HEK-293 Cells.

Quick Overview for MANSC1 Protein (AA 25-369) (His tag) (ABIN7275228)

Target: MANSC1 (MANSC Domain Containing 1 (MANSC1))

Protein Type: Recombinant

Biological Activity: Active

Origin: Mouse

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE

Product Details

Protein Characteristics: AA 25-369

Purification tag / Conjugate: This MANSC1 protein is labelled with His tag.

Purpose: Mouse MANSC1 Protein

Sequence: Gly25-Leu369

Characteristics: Recombinant Mouse MANSC1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly25-Leu369.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Mouse MANSC1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: MANSC1 (MANSC Domain Containing 1 (MANSC1))

Alternative Name: MANSC1

Background: MANSC1 contains 1 MANSC domain. MANSC is a seven-cysteine-containing domain present in animal membrane and extracellular proteins. MANSC (motif at N terminus with seven cysteines) is a novel domain with a well-conserved seven-cysteine motif that is present at the N terminus of membrane and extracellular proteins, including low-density lipoprotein receptor-related protein 11 (LRP-11), hepatocyte growth factor activator inhibitor 1 (HAI-1) and some uncharacterized proteins encoded by multicellular animals from Mollusca to Chordata. The MANSC domain in HAI-2 might function through binding with hepatocyte growth factor activator and matriptase[1].

Molecular Weight: 38.2 kDa. Due to glycosylation, the protein migrates to 58-110 kDa based on Bis-Tris PAGE result.

UniProt: Q9CR33