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MME Protein (AA 52-750) (His tag)

Recombinant MME protein expressed in HEK-293 Cells.
Catalog No. ABIN7275263

Quick Overview for MME Protein (AA 52-750) (His tag) (ABIN7275263)

Target

See all MME Proteins
MME (Membrane Metallo-Endopeptidase (MME))

Protein Type

Recombinant

Origin

  • 18
  • 5
  • 4
  • 1
Human

Source

  • 10
  • 8
  • 2
  • 2
  • 2
  • 2
HEK-293 Cells

Purity

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 52-750

    Purification tag / Conjugate

    This MME protein is labelled with His tag.

    Purpose

    Human CD10/MME Protein

    Sequence

    Tyr52-Trp750

    Characteristics

    Recombinant Human CD10/MME Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Tyr52-Trp750.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1EU per μg by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in 50 mM MES, 100 mM NaCl, 1 mM ZnCl2, 10 % Glycerol ( pH 6.5). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    MME (Membrane Metallo-Endopeptidase (MME))

    Alternative Name

    CD10

    Background

    CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression pattern depended on the histotypes of thyroid lesions. When possible metastatic tumours and non-epithelial tumours are excluded, high CD10 expression may be useful in determining whether a primary thyroid carcinoma includes an anaplastic component.

    Molecular Weight

    80.9 kDa. Due to glycosylation, the protein migrates to 81-110 kDa based on Tris-Bis PAGE result.

    UniProt

    P08473

    Pathways

    RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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