MUC1 Protein (AA 24-158) (Fc Tag)
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- Target See all MUC1 Proteins
- MUC1 (Mucin 1 (MUC1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-158
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MUC1 protein is labelled with Fc Tag.
- Purpose
- Human MUC1 Isoform Y Protein
- Sequence
- Ser24-Gly158
- Characteristics
- Recombinant Human MUC1 Isoform Y Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser24-Gly158.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Mucin 1 (MUC1) (AA 315-420) protein (GST tag)
MUC1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mucin 1 (MUC1) (AA 24-380) (Active) protein (Fc Tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Mucin 1 (MUC1) (AA 1095-1140) protein (His tag)MUC1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Mucin 1 (MUC1) (AA 1036-1156) protein (Fc Tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Mucin 1 (MUC1) (AA 1036-1156) protein (His tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Mucin 1 (MUC1) (AA 890-1158) protein (His tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Mucin 1 (MUC1) (AA 1036-1155) protein (His tag)MUC1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- MUC1 (Mucin 1 (MUC1))
- Alternative Name
- MUC1 (MUC1 Products)
- Background
- MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers.
- Molecular Weight
- 41.38 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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