Reticulon 4 Protein (RTN4) (AA 27-447) (His tag)
Quick Overview for Reticulon 4 Protein (RTN4) (AA 27-447) (His tag) (ABIN7275359)
Target
See all Reticulon 4 (RTN4) ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 27-447
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Purification tag / Conjugate
- This Reticulon 4 protein is labelled with His tag.
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Purpose
- Human NOGOR Protein
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Sequence
- Cys27-Ser447
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Characteristics
- Recombinant Human NOGOR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys27-Ser447.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human NOGOR, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-NOGOR Antibody, hFc Tag with the EC50 of 9ng/ml determined by ELISA. See testing image for detail.
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Reticulon 4 (RTN4) (AA 27-447) protein (His tag)
RTN4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Reticulon 4 (RTN4) (AA 1-1192) protein (His tag)custom-made RTN4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Reticulon 4 (RTN4) (AA 1-1162) protein (His tag)custom-made RTN4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Reticulon 4 (RTN4) (AA 27-447) protein (His tag)RTN4 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Reticulon 4 (RTN4) (AA 1-185) protein (His tag)RTN4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Reticulon 4 (RTN4) (AA 1-199) protein (GST tag)RTN4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Reticulon 4 (RTN4) (AA 1-1192) protein (GST tag)RTN4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- Reticulon 4 (RTN4)
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Alternative Name
- NOGOR
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Background
- NOGO Receptor 1 (RTN4R) regulates axonal growth, as well as axon regeneration after injury. The gene maps to the 22q11.2 schizophrenia susceptibility locus and is thus a strong functional and positional candidate gene.RTN4R may modulate the genetic risk or clinical expression of schizophrenia in a subset of patients and identify additional studies that will be necessary to clarify the role of RTN4R in psychiatric phenotypes.
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Molecular Weight
- 46.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
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UniProt
- Q9BZR6
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Pathways
- Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
Target
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