TNFRSF4 Protein (AA 29-216) (hFc Tag,Biotin)
Quick Overview for TNFRSF4 Protein (AA 29-216) (hFc Tag,Biotin) (ABIN7275388)
Target
See all TNFRSF4 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 29-216
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Purification tag / Conjugate
- This TNFRSF4 protein is labelled with hFc Tag,Biotin.
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Purpose
- Biotinylated Human OX40/TNFRSF4/CD134 Protein (Primary Amine Labeling)
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Sequence
- Leu29-Ala216
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Characteristics
- Recombinant Biotinylated Human OX40/TNFRSF4/CD134 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Leu29-Ala216.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Biotinylated Human OX40 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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Alternative Name
- OX40
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Background
- Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation, its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
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Molecular Weight
- 46.8 kDa. Due to glycosylation, the protein migrates to 72-75 kDa based on Bis-Tris PAGE result.
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UniProt
- P43489
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Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Target
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