PAI1 Protein (AA 24-402) (His tag)
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- Target See all PAI1 (SERPINE1) Proteins
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 24-402
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PAI1 protein is labelled with His tag.
- Purpose
- Human PAI-1 Protein
- Sequence
- Val24-Pro402
- Characteristics
- Recombinant Human PAI-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val24-Pro402.
- Purity
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 50 mM NaAC, 0.1M NaCl, 100 mM L-arginine ( pH 5.5).
- Storage
- -80 °C
- Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))
- Alternative Name
- PAI-1 (SERPINE1 Products)
- Background
- PAI-1 (plasminogen activator inhibitor-1) is a member of plasminogen cascade with an inhibitory role in plasmin activation. PAI-1 is an important regulator of the fibrinolytic process and levels of this antifibrinolytic protein are elevated in diabetes and insulin resistant states.
- Molecular Weight
- 43.86 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result.
- Pathways
- p53 Signaling, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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