PLAUR Protein (AA 23-114) (His tag)

Catalog No. ABIN7275403

This Recombinant PLAUR protein is expressed in HEK-293 Cells.

Quick Overview for PLAUR Protein (AA 23-114) (His tag) (ABIN7275403)

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Product Details

Protein Characteristics: AA 23-114

Purification tag / Conjugate: This PLAUR protein is labelled with His tag.

Purpose: Human uPAR/PLAUR Domain 1 Protein

Sequence: Leu23-Tyr114

Characteristics: Recombinant Human uPAR/PLAUR Domain 1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu23-Tyr114.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Human uPAR Domain 1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human uPAR Domain 1 is greater than 95% as determined by SEC-HPLC.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Alternative Name: uPAR

Background: The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.

Molecular Weight: 11.50 kDa. Due to glycosylation, the protein migrates to 17-25 kDa based on Bis-Tris PAGE result.

UniProt: Q03405

Pathways: Inositol Metabolic Process