PLAUR Protein (AA 23-305) (hFc Tag)
Quick Overview for PLAUR Protein (AA 23-305) (hFc Tag) (ABIN7275406)
Target
See all PLAUR ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 23-305
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Purification tag / Conjugate
- This PLAUR protein is labelled with hFc Tag.
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Purpose
- Human uPAR/PLAUR Protein
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Sequence
- Leu23-Gly305
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Characteristics
- Recombinant Human uPAR/PLAUR Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Leu23-Gly305.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human PLAU, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Human uPAR, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA.,Human uPAR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human uPAR is greater than 95% as determined by SEC-HPLC.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
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Storage
- -80 °C
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Storage Comment
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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Alternative Name
- uPAR
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Background
- The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
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Molecular Weight
- 58.2 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
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UniProt
- Q03405
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Pathways
- Inositol Metabolic Process
Target
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