PDGFRB Protein (AA 33-531) (His tag)
Quick Overview for PDGFRB Protein (AA 33-531) (His tag) (ABIN7275443)
Target
See all PDGFRB ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 33-531
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Purification tag / Conjugate
- This PDGFRB protein is labelled with His tag.
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Purpose
- Cynomolgus PDGF R beta/CD140b Protein
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Sequence
- Leu33-Lys531
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Characteristics
- Recombinant Cynomolgus PDGF R beta/CD140b Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu33-Lys531.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1EU per μg by the LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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Alternative Name
- PDGF R beta
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Background
- Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity after cerebral ischemia and therefore represents a novel potential therapeutic target.
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Molecular Weight
- 57.49 kDa. Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.
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UniProt
- A0A2K5TUS0
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
Target
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