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ROR2 Protein (AA 34-403) (His-Avi Tag)

This Recombinant ROR2 protein is produced in HEK-293 Cells.
Catalog No. ABIN7275534

Quick Overview for ROR2 Protein (AA 34-403) (His-Avi Tag) (ABIN7275534)

Target

See all ROR2 Proteins
ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Protein Type

Recombinant

Origin

  • 17
  • 4
  • 1
  • 1
Human

Source

  • 13
  • 3
  • 2
  • 2
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 34-403

    Purification tag / Conjugate

    This ROR2 protein is labelled with His-Avi Tag.

    Purpose

    Human ROR2/NTRKR2 Protein

    Sequence

    Val34-Gly403

    Characteristics

    Recombinant Human ROR2/NTRKR2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Val34-Gly403.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human ROR2, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-ROR2 Antibody, hFc Tag with the EC50 of 8ng/ml determined by ELISA. See testing image for detail.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

    Alternative Name

    ROR2

    Background

    ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.

    Molecular Weight

    44.2 kDa. Due to glycosylation, the protein migrates to 54-58 kDa based on Tris-Bis PAGE result.

    UniProt

    A1L4F5

    Pathways

    RTK Signaling, WNT Signaling
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