Syndecan 1 Protein (SDC1) (AA 23-254) (His tag)

Catalog No. ABIN7275681

Product Details

Target: Syndecan 1 (SDC1)

Protein Type: Recombinant

Protein Characteristics: AA 23-254

Origin: Rabbit

Source: HEK-293 Cells

Purification tag / Conjugate: This Syndecan 1 protein is labelled with His tag.

Purpose: Rabbit Syndecan-1 Protein

Sequence: Leu23-Gly254

Characteristics: Recombinant Rabbit Syndecan-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu23-Gly254.

Purity: > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Syndecan 1 (SDC1)

Alternative Name: Syndecan-1 (SDC1 Products)

Background: CD138 (syndecan-1, Sdc-1) is a member of the syndecan family that comprises heparan sulfate proteoglycans. CD138 is significant for cell-cell and cell-matrix interactions.CD138 plays a crucial role in carcinogenesis and is an attractive target for anticancer treatment with heparanase inhibitors and anti-CD138 antibodies for immunotherapy.

Molecular Weight: 24.57 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.

NCBI Accession: XP_008252990

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism