TGFBR1 Protein (AA 34-125) (mFc-Avi Tag)
Quick Overview for TGFBR1 Protein (AA 34-125) (mFc-Avi Tag) (ABIN7275720)
Target
See all TGFBR1 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 34-125
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Purification tag / Conjugate
- This TGFBR1 protein is labelled with mFc-Avi Tag.
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Purpose
- Non-biotinylated Human TGFBR1 Protein
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Sequence
- Leu34-Glu125
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Characteristics
- Recombinant Human TGFBR1 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at the C-Terminus.It contains Leu34-Glu125.
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Sterility
- 0.22 μm filtered
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Endotoxin Level
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Human TGFBR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human TGFBR1 is greater than 95% as determined by SEC-HPLC.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Expiry Date
- 12 months
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- TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))
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Alternative Name
- TGFBR1
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Background
- Transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR-98-5p. miR-98-5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells.
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Molecular Weight
- 38.2 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Bis-Tris PAGE result.
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UniProt
- P36897
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Pathways
- Growth Factor Binding
Target
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