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TGFBR1 Protein (AA 34-125) (mFc-Avi Tag)

This Recombinant TGFBR1 protein is produced in HEK-293 Cells.
Catalog No. ABIN7275720
$417.68
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Quick Overview for TGFBR1 Protein (AA 34-125) (mFc-Avi Tag) (ABIN7275720)

Target

See all TGFBR1 Proteins
TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 17
  • 5
  • 2
  • 1
  • 1
Human

Source

  • 7
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

Purity

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • Protein Characteristics

    AA 34-125

    Purification tag / Conjugate

    This TGFBR1 protein is labelled with mFc-Avi Tag.

    Purpose

    Non-biotinylated Human TGFBR1 Protein

    Sequence

    Leu34-Glu125

    Characteristics

    Recombinant Human TGFBR1 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at the C-Terminus.It contains Leu34-Glu125.

    Sterility

    0.22 μm filtered

    Endotoxin Level

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Human TGFBR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human TGFBR1 is greater than 95% as determined by SEC-HPLC.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

    Buffer

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    TGFBR1 (Transforming Growth Factor, beta Receptor 1 (TGFBR1))

    Alternative Name

    TGFBR1

    Background

    Transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR-98-5p. miR-98-5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells.

    Molecular Weight

    38.2 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Bis-Tris PAGE result.

    UniProt

    P36897

    Pathways

    Growth Factor Binding
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