LI Cadherin Protein (Biotin,His-Avi Tag)
Quick Overview for LI Cadherin Protein (Biotin,His-Avi Tag) (ABIN7316790)
Target
See all LI Cadherin ProteinsProtein Type
Origin
Source
Purity
Grade
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Purification tag / Conjugate
- This LI Cadherin protein is labelled with Biotin,His-Avi Tag.
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Purpose
- Biotinylated Human Cadherin-17 / CDH17 Protein, His,Avitag™ (MALS verified)
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Sequence
- Gln 23 - Met 787
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Characteristics
- Biotinylated Human Cadherin-17, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Met 787 (Accession # Q12864-1).
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Endotoxin Level
- 1.0 EU per μg
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LI Cadherin (AA 23-787) protein (His tag)
Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LI Cadherin (AA 23-787) protein (Fc Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LI Cadherin (AA 23-787) protein (His-Avi Tag,Biotin)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LI Cadherin (AA 26-786) protein (His tag)Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LI Cadherin (AA 1-795) protein (His tag)Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
LI Cadherin (AA 567-777) protein (Fc Tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LI Cadherin (AA 30-244) protein (His tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
LI Cadherin (AA 23-667) protein (His tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
LI Cadherin (AA 23-787) protein (FITC,His tag)Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
LI Cadherin (AA 567-667) protein (mFc Tag)Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Comment
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This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 88.6 kDa. The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 20 mM Tris, 150 mM NaCl, pH 8.0
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Storage
- -20 °C
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Storage Comment
- -20°C
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- LI Cadherin
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Alternative Name
- Cadherin-17
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Background
- Synonyms:Cadherin-17,CDH17,HPT-1, LI-cadherin,Description:Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
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Molecular Weight
- 88.6 kDa
Target
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