TRDC Protein (His tag)

Catalog No. ABIN7448092

This Recombinant TRDC protein is produced in HEK-293 Cells.

Quick Overview for TRDC Protein (His tag) (ABIN7448092)

Target: TRDC (T Cell Receptor delta Constant (TRDC))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: 90,00 %

Product Details

Purification tag / Conjugate: This TRDC protein is labelled with His tag.

Purpose: Human TRDC Protein, His Tag

Sequence: Ser 1 - Val 129

Characteristics: Human TRDC, His Tag is expressed from human 293 cells (HEK293). It contains AA Ser 1 - Val 129 (Accession # B7Z8K6-1).

Endotoxin Level: 1.0 EU per μg

Application Details

Comment:

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.4 kDa. The protein migrates as 27-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Storage Comment: -20°C

Target Details

Target: TRDC (T Cell Receptor delta Constant (TRDC))

Alternative Name: TRDC

Background: Synonyms:TRDC,Description:The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain. Each polypeptide chain consists of a variable and a constant region. TRDC is the constant region of T-cell receptor (TCR) delta chain. It recognizes the non-peptide antigens frequently expressed at the epithelial boundaries, which means the antigens activating γδ T cells are mostly MHC independent. A wide range of γδ T cell functions have been described in humans and mice, including skin and mucosal epithelial wound repair, induction of tolerance, cytotoxicity and the production of various cytokines that regulate immune responses.

Molecular Weight: 16.4 kDa