MBL2 Protein (AA 21-248) (His tag)
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- Target See all MBL2 Proteins
- MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-248
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MBL2 protein is labelled with His tag.
- Purpose
- Human MBL2/Mannan Binding Lectin Protein
- Sequence
- Glu21-Ile248
- Characteristics
- Recombinant Human MBL2/Mannan Binding Lectin Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Ile248.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))
- Alternative Name
- MBL2 (MBL2 Products)
- Background
- Mannan-binding lectin (MBL) is a vital element in the host innate immune system, which is primarily produced by the liver and secreted into the circulation.It is present in serum and may bind to a plethora of microbial pathogens and mediate opsonization of these by complement-dependent and/or independent mechanisms.
- Molecular Weight
- 25.11 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
- UniProt
- P11226
- Pathways
- Complement System, Positive Regulation of Immune Effector Process
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