GPR75 Protein (AA 1-46) (Fc Tag)

Catalog No. ABIN7490707

This Recombinant GPR75 protein is produced in HEK-293 Cells.

Quick Overview for GPR75 Protein (AA 1-46) (Fc Tag) (ABIN7490707)

Target: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 1-46

Purification tag / Conjugate: This GPR75 protein is labelled with Fc Tag.

Purpose: Recombinant human GPR75 Protein with C-terminal Human Fc tag

Specificity: GPR75(Met1-Thr46) hFc(Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Alternative Name: GPR75

Background: Probable G-protein coupled receptor 75
GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002]

Molecular Weight: predicted molecular mass of 31.0 kDa after removal of the signal peptide. The apparent molecular mass of GPR75-hFc is 35-55 kDa due to glycosylation.

UniProt: O95800