Ectodysplasin A Protein (EDA) (Fc Tag)
Quick Overview for Ectodysplasin A Protein (EDA) (Fc Tag) (ABIN7490962)
Target
See all Ectodysplasin A (EDA) ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This Ectodysplasin A protein is labelled with Fc Tag.
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Purpose
- Recombinant Human EDA Protein with N-terminal human Fc tag
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Specificity
- HFc (Glu99-Ala330) EDA (Ser160-Ser391)
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Characteristics
- Extracellular Domain Protein
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Purification
- Purified from cell culture supernatant by affinity chromatography
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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Expiry Date
- 12 months
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- Ectodysplasin A (EDA)
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Alternative Name
- EDA
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Background
- The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Molecular Weight
- predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-EDA is 55-70 kDa due to glycosylation.
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UniProt
- Q92838
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Pathways
- Tube Formation
Target
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