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Ectodysplasin A Protein (EDA) (Fc Tag)

This Recombinant Ectodysplasin A protein is expressed in HEK-293 Cells.
Catalog No. ABIN7490962

Quick Overview for Ectodysplasin A Protein (EDA) (Fc Tag) (ABIN7490962)

Target

See all Ectodysplasin A (EDA) Proteins
Ectodysplasin A (EDA)

Protein Type

Recombinant

Origin

  • 7
  • 5
  • 1
Human

Source

  • 4
  • 3
  • 2
  • 2
  • 1
HEK-293 Cells

Purity

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Purification tag / Conjugate

    This Ectodysplasin A protein is labelled with Fc Tag.

    Purpose

    Recombinant Human EDA Protein with N-terminal human Fc tag

    Specificity

    HFc (Glu99-Ala330) EDA (Ser160-Ser391)

    Characteristics

    Extracellular Domain Protein

    Purification

    Purified from cell culture supernatant by affinity chromatography
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
    Price starts at $16,231.82
    Expression System Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Expiry Date

    12 months
  • Target

    Ectodysplasin A (EDA)

    Alternative Name

    EDA

    Background

    The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

    Molecular Weight

    predicted molecular mass of 50.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-EDA is 55-70 kDa due to glycosylation.

    UniProt

    Q92838

    Pathways

    Tube Formation
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