Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IL-13 Protein (AA 35-146) (Fc Tag)

IL13 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7491185
  • Target See all IL-13 (IL13) Proteins
    IL-13 (IL13) (Interleukin 13 (IL13))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 35-146
    Origin
    • 22
    • 14
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 28
    • 13
    • 8
    • 7
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL-13 protein is labelled with Fc Tag.
    Purpose
    Recombinant human IL13(35-146) protein with C-terminal human Fc tag
    Specificity
    IL13 (Gly35-Asn146) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product IL13 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    IL-13 (IL13) (Interleukin 13 (IL13))
    Alternative Name
    IL13 (IL13 Products)
    Background
    This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
    Molecular Weight
    predicted molecular mass of 38.4 kDa after removal of the signal peptide. The apparent molecular mass of IL13(35-146)-hFc is 33-53 kDa due to glycosylation.
    UniProt
    P35225
    Pathways
    JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
You are here:
Support