LAMP3 Protein (AA 28-381) (His tag)

Catalog No. ABIN7491217

This Recombinant LAMP3 protein is expressed in HEK-293 Cells.

Quick Overview for LAMP3 Protein (AA 28-381) (His tag) (ABIN7491217)

Target: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Affinity Measurement (AM), Antibody Drug Assay (ADA), Immunoassay (IA), Screening Assay (ScA)

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Product Details

Protein Characteristics: AA 28-381

Purification tag / Conjugate: This LAMP3 protein is labelled with His tag.

Purpose: Recombinant human LAMP3 protein with C-terminal 6xHis tag

Specificity: LAMP3(Lys28-Thr381) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Application Details

Application Notes: Extracellular Domain Proteins (ECD) can be used as:

• Immunogens for antibody drug development
• Reagents used for CAR-T positive cell monitoring
• Reagents for antibody screening and functional testing
• Reagents for antibody affinity measurement

Comment:

The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Alternative Name: LAMP3

Background: CD208,DC-LAMP,DC LAMP,DCLAMP,LAMP,LAMP-3,TSC403
Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]

Molecular Weight: predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of LAMP3-His is 35-130 kDa due to glycosylation.

UniProt: Q9UQV4